Educational Background
Ph.D. in Microbiology, College of Biological Sciences, China Agricultural University, September 2005 - June 2010
B.S. in Biotechnology, School of Life Sciences, Shandong Normal University, September 2001 - June 2005
Research Experience
Professor, College of Biological Sciences, China Agricultural University, December 2019 - Present
Associate Professor, College of Biological Sciences, China Agricultural University, January 2014 - November 2019
Lecturer, College of Biological Sciences, China Agricultural University, July 2010 - December 2013
Visiting Scholar, University of California, Davis, August 2017 - October 2018
Visiting Scholar, University of California, Berkeley, March 2013 - August 2013
I primarily focus on how viruses infect plant hosts and how host plants defend themselves against virus infections. I use a combination of cell biology, genetics, biochemistry, and proteomics approaches to investigate the mechanisms underlying virus-host interactions, including virus replication mechanisms and movement as well as R gene-mediated innate immune response to plant virus infection, among others. I have developed several plant virus-based vectors for virus-induced gene silencing or the delivery of guide RNAs, which provide alternative and effective tools for examining gene functions in plants. Up to now, I have published more than 50 SCI papers in various journals, including PNAS, EMBO J, Plant Cell, Nature Communication, Molecular Plant, New Phytologist, Journal of Virology, to name a few.
Representative papers (*Corresponding author, #equal contribution)
see more details by loging in https://orcid.org/0000-0002-6790-1044
2023
1. Dingliang Zhang, Zongyu Gao, He Zhang, Yizhou Yang, Xinxin Yang, Xiaofei Zhao, Hailong Guo, Ugrappa Nagalakshmi, Dawei Li, Savithramma P. Dinesh-Kumar*, Yongliang Zhang*. The MAPK-Alfin-like 7 module negatively regulates ROS scavenging genes to promote NLR-mediated immunity. PNAS, 2023, 120(3): e2214750120. (Trends in Plant Science Spotlight, https://www.cell.com/trends/plant-science/fulltext/S1360-1385(23)00049-3).
2. Qianshen Zhang#, Zhiyan Wen#, Xin Zhang#, Jiajie She, Xiaoling Wang, Zongyu Gao, Ruiqi Wang, Xiaofei Zhao, Zhen Su, Zhen Li, Dawei Li, Xiaofeng Wang, Yongliang Zhang*. RETICULON-LIKE PROTEIN B2 is a pro-viral factor co-opted for the biogenesis of viral replication organelles in plants. Plant Cell, 2023, https://doi.org/10.1093/plcell/koad146.
3. Jianguo Wu#, Yongliang Zhang#, Fangfang Li#, Xiaoming Zhang#, Jian Ye, Taiyun Wei, Zhenghe Li, Xiaorong Tao, Feng Cui, Xianbing Wang, Lili Zhang, Fei Yan, Shifang Li, Yule Liu, Dawei Li, Xueping Zhou*, Yi Li*. Plant virology in the 21st century in China: Recent advances and future directions. Journal of Integrative Plant Biology., DOI: 10.1111/jipb.13580.
2022
4. Qiuhong Wu#, Yu Cui#, Xuejiao Jin#, Guoxin Wang#, Lijie Yan#, Chenchen Zhong, Meihua Yu, Wenli Li, Yong Wang, Ling Wang, Hao Wang, Chen Dang, Xinyu Zhang, Yongxing Chen, Panpan Zhang, Xiaofei Zhao, Jiajie Wu, Daolin Fu, Lanqin Xia, Eviatar Nevo, John Vogel, Naxin Huo, Dawei Li, Yong Q. Gu, Andrew O. Jackson*, Yongliang Zhang*, and Zhiyong Liu*. The CC‐NB‐LRR protein BSR1 from Brachypodium confers resistance to Barley stripe mosaic virus in gramineous plants by recognizing TGB1 movement protein. New Phytologist, 2022, 236: 2233-2248.
5. Zongyu Gao, Dingliang Zhang, Xiaoling Wang, Xin Zhang, Zhiyan Wen, Qianshen Zhang, Dawei Li, Savithramma P. Dinesh-Kumar, Yongliang Zhang*. Coat proteins of necroviruses target 14-3-3a to subvert MAPKKKα-mediated antiviral immunity in plants. Nature Communications, 2022, 13:716. (Editors’ Highlight; Web of Science Highly cited paper).
6. Zhaolei Li#, Xinxin Yang#, Wenli Li, Zhiyan Wen, Jiangning Duan, Zhihao Jiang, Dingliang Zhang, Xialin Xie, Xueting Wang, Fangfang Li, Dawei Li, Yongliang Zhang*. SAMDC3 enhances resistance to Barley stripe mosaic virus by promoting the ubiquitination and proteasomal degradation of viral γb protein. New Phytologist, 2022, 234: 618-633.
2021年以前
7. Yongliang Zhang*, Gaoyuan Song, Neeraj K. Lal, Ugrappa Nagalakshmi, Yuanyuan Li, Wenjie Zheng, Pin-jui Huang, Tess C. Branon, Alice Y. Ting, Justin W. Walley* and Savithramma P. Dinesh-Kumar*. TurboID-based proximity labeling reveals that UBR7 is a regulator of N NLR immune receptor-mediated immunity. Nature Communications, 2019, 10: 3252. (F1000Prime; Web of Science Highly cited paper).
8. Tingdong Li#, Jiacheng Hu#, Yu Sun, Boshu Li, Dingliang Zhang, Wenli Li, Jinxing Liu, Dawei Li, Caixia Gao, Yongliang Zhang*, Yanpeng Wang*. Highly efficient heritable genome editing in wheat using an RNA virus and bypassing tissue culture. Molecular Plant, 2021, 14: 1787-1798. (Best paper of Molecular Plant 2021; Web of Science Highly cited paper, Hot topic paper)
9. Xinxin Yang#, Zhiyan Wen#, Dingliang Zhang, Zhen Li, Dawei Li, Ugrappa Nagalakshmi, Savithramma P. Dinesh-Kumar*, Yongliang Zhang*. Proximity labeling: An emerging tool for probing in planta molecular interactions, Plant Communications, 2021, 2: 100137. (Best paper of Plant Communications 2021)
10. Zhihao Jiang, Kun Zhang, Zhaolei Li, Zhenggang Li, Meng Yang, Xuejiao Jin, Qing Cao, Xueting Wang, Ning Yue, Dawei Li, Yongliang Zhang*. The Barley stripe mosaic virus γb protein promotes viral cell-to-cell movement by enhancing ATPase-mediated assembly of ribonucleoprotein movement complexes. PLoS Pathogens, 2020, 16(7): e1008709.
11. Kun Zhang#, Yongliang Zhang#, Meng Yang, Songyu Liu, Zhenggang Li, Xianbing Wang, Chenggui Han, Jialin Yu, Dawei Li*. The Barley stripe mosaic virus γb protein promotes chloroplast-targeted replication by enhancing unwinding of RNA duplexes. PLoS Pathogens, 2017, 13(4): e1006319.
12. Xuejiao Jin, Zhihao Jiang, Kun Zhang, Pengfei Wang, Xiuling Cao, Ning Yue, Xueting Wang, Xuan Zhang, Yunqin Li, Dawei Li, Byung-Ho Kang, and Yongliang Zhang*. Three-dimensional analysis of chloroplast structures associated with virus infection. Plant Physiology, 2018, 176: 282-294.
13. Xiuling Cao, Xuejiao Jin, Xiaofeng Zhang, Ying Li, Chunyan Wang, Xianbing Wang, Jian Hong, Xiaofeng Wang, Dawei Li, Yongliang Zhang*. Morphogenesis of the ER membrane-invaginated vesicles during Beet black scorch virus infection: The role of auxiliary replication protein and new implications of three-dimensional architecture. Journal of Virology, 2015, 89(12): 6184-6195. (Spotlight).
14. Yongliang Zhang, Jiang Li, Heng Pu, Jin Jin, Xiaofeng Zhang, Mingkuan Chen, Bin Wang, Chenggui Han, Jialin Yu, Dawei Li. Development of Tobacco necrosis virus A as a vector for efficient and stable expression of FMDV VP1 peptides. Plant Biotechnology Journal, 2010, 8(4): 506-523.
15. Xueting Wang, Juncai Ma, Xuejiao Jin, Ning Yue, Peng Gao, Keith Ka Ki Mai, Xian-Bing Wang, Dawei Li, Byung-Ho Kang* and Yongliang Zhang*. Three-dimensional reconstruction and comparisons of vacuolar membranes associated with virus infections. Journal of Integrative Plant Biology, 2021, 63(2): 353–364. (Covery story)
16. Zongyu Gao, Heng Pu, Jingyuan Liu, Xiaoling Wang, Chenchen Zhong, Ning Yue, Ziding Zhang, Xian-Bing Wang, Chenggui Han, Jialin Yu, Dawei Li, Yongliang Zhang*. Tobacco necrosis virus-AC single coat protein amino acid substitutions determine host-specific systemic infections of Nicotiana benthamiana and soybean. Molecular Plant-Microbe Interactions, 2021, 34(1): 49–61. (Spotlight)
17. Deshui Liu#, Lindan Shi#, Chenggui Han, Jialin Yu, Dawei Li, Yongliang Zhang*. Validation of reference genes for gene expression studies in virus-infected Nicotiana benthamiana using quantitative real-time PCR. PLoS ONE, 2012, 7(9): e46451. (Web of Science Highly cited paper).
