With global warming, heat stress adversely affects plant growth, development, and crop yield. However, it remains unclear how plants perceive and respond to heat stress. We are using genetic, biochemical and molecular approaches to identify key components essential for heat stress signaling pathway and investigate the functions of these components in heat responses.
(*Corresponding author; #These authors contributed equally)
1. Wang X#, Zhang X#, Song C, Gong Z, Yang S, Ding Y* (2023) PUB25 and PUB26 dynamically modulate ICE1 stability via differential ubiquitination during cold stress in Arabidopsis. Plant Cell 35:3585-3603
2. Sun Z, Feng Z, Ding Y, Qi Y, Jiang S, Li Z, Wang Y, Qi J, Song C, Yang S, Gong Z* (2022) RAF22, ABI1 and OST1 form a dynamic interactive network that optimizes plant growth and responses to drought stress in Arabidopsis. Mol Plant 7:1192-1210
3. Ding Y*, Yang S* (2022) Surviving and thriving: How plants perceive and respond to temperature stress. Dev Cell 57:947-958 (Highly cited in ESI)
4. Ding Y*#, Yang H#, Wu S, Fu D, Li M, Gong Z, Yang S* (2022) CPK28-NLP7 module integrates cold-induced Ca2+ signal and transcriptional reprogramming in Arabidopsis. Sci Adv 8:eabn7901 (Selected for F1000 Prime; Highlighted with a Spotlight article in Nat Plants)
5. Chen R#, Deng Y#, Ding Y#, Guo J#, Qiu J#, Wang B#, Wang C#, Xie Y#, Zhang Z#, Chen J, Chen L, Chu C, He G, He Z, Huang Y, Xing Y, Yang S, Xie D*, Liu YG*, Li J* (2021) Rice functional genomics: decades’ efforts and roads ahead. Sci China Life Sci 65: 33-92. (Highly cited in ESI)
6. Song Y#, Zhang X#, Li M#, Yang H, Fu D, Lv J, Ding Y, Gong Z, Shi Y*, Yang S (2021) The direct targets of CBFs: in cold stress response and beyond. J Integr Plant Biol 63:1874-1887. (Highly cited in ESI)
7. Lv J, Liu J, Ming Y, Shi Y, Song C, Gong Z, Yang S, Ding Y* (2021) Reciprocal regulation between the negative regulator PP2CG1 phosphatase and the positive regulator OST1 kinase confers cold response in Arabidopsis. J Integr Plant Biol 63: 1568-1587.
8. Chen X#, Ding Y#, Yang Y#, Song C, Wang B, Yang S, Guo Y, Gong Z* (2021) Protein kinases in plant responses to drought, salt, and cold stress. J Integr Plant Biol 63: 53-78. (Highly cited in ESI)
9. Liu Q, Ding Y, Shi Y, Ma L, Wang Y, Song C, Wilkins KA, Davies JM, Knight H, Knight MR, Gong Z, Guo Y, Yang S* (2021) The calcium transporter ANNEXIN1 mediates cold-induced calcium signaling and freezing tolerance in plants. EMBO J 40: e104559. (Selected for F1000 Prime)
10. Gong Z#, Xiong L#, Shi H#, Yang S#, Herrera-Estrella LR#, Xu G#, Chao DY#, Li J, Wang PY, Qin F, Li J, Ding Y, Shi Y, Wang Y, Yang Y, Guo Y*, Zhu JK* (2020) Plant abiotic stress response and nutrient use efficiency. Sci China Life Sci 63, 635-674. (Highly cited in ESI)
11. Ding Y, Shi Y, Yang S* (2020) Molecular regulation of plant responses to environmental temperatures. Mol Plant13:544-564. (Highly cited in ESI)
12. Ye K#, Li H#, Ding Y, Shi Y, Song C, Gong Z, Yang S* (2019) BIN2 negatively regulates ICE1 stability in response to cold stress in Arabidopsis. Plant Cell 31: 2682-2696. (Highly cited in ESI)
13. Wang X, Ding Y, Li Z, Shi Y, Wang J, Hua J, Gong Z, Zhou JM, Yang S* (2019) PUB25 and PUB26 promote plant freezing tolerance by degrading the cold signaling negative regulator MYB15. Dev Cell 51: 222-235. (Selected for F1000 Prime)
14. Ding Y, Lv J, Shi Y, Gao J, Hua J, Song C, Gong Z, Yang S* (2019) EGR2 phosphatase regulates OST1 kinase activity and freezing tolerance in Arabidopsis. EMBO J 38: e99819. (Selected for F1000 Prime)
15. Ding Y#, Shi Y#, Yang S* (2019) Advances and challenges in uncovering cold tolerance regulatory mechanisms in plants. New Phytol 222: 1690-1704. (Highly cited in ESI)
16. Shi Y#, Ding Y#, Yang S* (2018) Molecular regulation of CBF signaling in cold acclimation. Trends Plant Sci 23: 623-637. (Highly cited in ESI)
17. Ding Y, Jia Y, Shi Y, Song C, Gong Z, Yang S* (2018) OST1-mediated BTF3L phosphorylation positively regulates CBFs during plant cold responses. EMBO J 37: e98228.
18. Wang K#, He J#, Zhao Y, Wu T, Zhou X, Ding Y, Kong L, Wang X, Wang Y, Li J, Song CP, Wang B, Yang S, Zhu JK, Gong Z* (2018) EAR1 negatively regulates ABA signaling by enhancing 2C protein phosphatase activity. Plant Cell 30: 815-834.
19. Li H, Ding Y, Shi Y, Zhang X, Zhang S, Gong Z, Yang S* (2017) MPK3- and MPK6-mediated ICE1 phosphorylation negatively regulates ICE1 stability and freezing tolerance in Arabidopsis. Dev Cell 43: 630-642. (Highlighted with a Preview article in Dev Cell and a Spotlight article in Trends Plant Sci; Selected for F1000 Prime; 植物学报热点评)
20. Liu Z, Jia Y, Ding Y, Shi Y, Zhang X, Li Z, Guo Y, Gong Z, Yang S* (2017) Plasma membrane CRPK1-mediated phosphorylation of 14-3-3 proteins induces their nuclear import to fine-tune CBF signaling during cold response. Mol Cell 66: 117-128. (Highlighted with a Preview article in Mol Cell; Selected for F1000 Prime)
21. Zhang Z#, Li J#, Pan Y#, Li J#, Zhou L#, Shi H#, Zeng Y#, Guo H, Yang S, Zheng W, Yu J, Sun X, Li G, Ding Y, Ma L, Shen S, Dai L, Zhang H, Yang S, Guo Y, Li Z* (2017) Natural variation in CTB4a enhances rice adaptation to cold habitats. Nat Commun 8:14788. (Highly cited in ESI)
22. Zhang Y#, Wang Y#, Liu J, Ding Y, Wang S, Zhang X, Liu Y, Yang S* (2017) Temperature-dependent autoimmunity mediated by chs1 requires its neighboring TNL gene SOC3. New Phytol 213:1330-1345.
23. Jia Y, Ding Y, Shi Y, Zhang X, Gong Z, Yang S* (2016) The cbfs triple mutants reveal the essential functions of CBFs in cold acclimation and allow the definition of CBF regulons in Arabidopsis. New Phytol 212: 345-353. (Highlighted with a Commentary article in New Phytol; Highly cited in ESI)
24. Yu F, Lou L, Tian M, Li Q, Ding Y, Wu Y, Belda-Palazon B, Rodrigue P L, Yang S, Xie Q* (2016) ESCRT-I component VPS23A affects ABA signaling by recognizing ABA receptors for endosomal degradation. Mol Plant 9: 1570-1582.
25. Ding Y, Li H, Zhang X, Xie Q, Gong Z, Yang S* (2015) OST1 kinase modulates freezing tolerance by enhancing ICE1 stability in Arabidopsis. Dev Cell 32: 278-289. (Highlighted with a Preview article in Dev Cell; Highlighted with an article in SCIENCE CHINA Life Sciences; 植物学报热点评; Highly cited in ESI)
26. Kong L, Cheng J, Zhu Y, Ding Y, Meng J, Chen Z, Xie Q, Guo Y, Li J, Yang S, Gong Z* (2015) Degradation of the ABA co-receptor ABI1 by PUB12/13 U-box E3 ligases. Nat Commun 6: 8630. (Highly cited in ESI)
27. Shi Y#, Ding Y#, Yang S* (2015) Cold signal transduction and its interplay with phytohormones during cold acclimation. Plant Cell Physiol 56: 7-15. (Highly cited in ESI)
